A REVIEW OF CABOZANTINIB

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Abbott Laboratories has formulated a thienopyridone compound, A-769662, which leads to allosteric activation of purified AMPK in mobile-free assays.98 This compound shows lots of the metabolic effects that would be envisioned with AMPK activation in vivo (boost in Excess fat oxidation in typical rats; decreases in entire body fat, plasma glucose/tr